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Articles

Date of Publish: 31/10/1996

Mercury-Specific Lymphocytes: An indication of Mercury Allergy in Man

Stejskal V, Forsbeck M et al, Journal of Clinical Immunology, Vol. 16, No 1, 1996
In this study, 18 patients with oral lichen planus (OLP), adjacent to amalgam fillings, were tested in vitro with MELISA® and with patch test. Some of the patients also suffered from systemic symptoms such as arthralgia, myalgia, eczema, diabetes and chronic malaise. Twenty healthy subjects with amalgam fillings and twelve healthy amalgam-free subjects served as controls. The results show that the patient group had significantly higher reactivity to inorganic mercury, a corrosion product of amalgam, compared to the control group. Removal of amalgam fillings resulted in the disappearance of oral mucosal changes, thus indicating a causal relationship.

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