Date of Publish: 10/08/1994

MELISA® - an in vitro tool for the study of metal allergy

Stejskal V, Cederbrant K, Lindvall A, Forsbeck M, Toxicology In Vitro (an International Journal Published in association with BIBRA), 1994, vol 8, p. 991-1000
This article describes how to diagnose allergy to various mercury compounds such as thimerosal, phenyl mercury and inorganic mercury. Since these mercurials are immunologically non-cross reacting, it is possible by MELISA® not only to determine the existence of mercury allergy but also the source of sensitization. Thimerosal, a component of vaccines, eye drops and nose drops, is ethyl mercury salt of thiosalicylic acid. Strong allergenic properties of thimerosal have been known for years, as reflected by the presence of thimerosal as a standard component of patch-tests.

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